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Could GLP-1 drugs like Ozempic or Wegovy compete with specialized PWS therapies

Removal of bioactive GLP-1 is a consequence of N-terminal proteolysis catalyzed by dipeptidylpeptidase IV (DPP IV or DPP4)

Use between 1 to 2.5 ml of solution for reconstitution unless specific studies confirm that a higher volume is safe

doi: 10.1016/j.pneurobio.2005.06.004

The results show that chemical stress in the ALE strategy is effective in increasing metabolite production and stress tolerance of filamentous fungi and can pave the way for improving industrial strains